Peptides that self-assemble into nanofibrous networks provide a prominent alternative to traditional biomaterials for fabricating scaffolds for use in regenerative medicine and other biomedical applications. Such scaffolds can be modified by decorating the peptide backbone with other bioactives such as cell specific adhesion peptides, growth factors and enzyme cleavable sequences. They can be designed to mimic the three-dimensional (3D) structural features of native ECM and can serve as regeneration templates for specific target tissues or organs.
Regenerative medicine products under development by Ferentis:
| Skin/wound healing template |
Reference:
Ravichandran, R., Griffith, M., Phopase, J.
Mater. Chem. B. 2: 8466-8478